drugset / Trial / NCT00385684
Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)
RandomizedCrossoverQuadruple-blindTreatment
Summary
The purpose of this study was to determine whether a low dose an opiate pain medication is effective for the treatment of discomfort in patients with advanced dementia. The study medication was also known as Lortab and contained both a narcotic pain medication and acetaminophen (the same pain medication as contained in Tylenol). This study was an eight-week long clinical trial for discomfort among veterans with advanced dementia who were admitted to a Nursing Home Care Unit (NHCU) at the Tuscaloosa VA Medical Center.
Timeline
- Start
- 2007-10
- Primary completion
- 2011-12
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 167 mg | — |
| Subject | Acetaminophen | Small molecule | 500 mg | — |
| Subject | Hydrocodone | Unknown | 2.5 mg | — |
| Subject | Hydrocodone | Unknown | 5 mg | — |