drugset / Trial / NCT00385684

Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)

NCT00385684

Phase 4 Completed 11 enrolled VA Office of Research and Development
RandomizedCrossoverQuadruple-blindTreatment

Summary

The purpose of this study was to determine whether a low dose an opiate pain medication is effective for the treatment of discomfort in patients with advanced dementia. The study medication was also known as Lortab and contained both a narcotic pain medication and acetaminophen (the same pain medication as contained in Tylenol). This study was an eight-week long clinical trial for discomfort among veterans with advanced dementia who were admitted to a Nursing Home Care Unit (NHCU) at the Tuscaloosa VA Medical Center.

Timeline

Start
2007-10
Primary completion
2011-12
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 167 mg
Subject Acetaminophen Small molecule 500 mg
Subject Hydrocodone Unknown 2.5 mg
Subject Hydrocodone Unknown 5 mg