drugset / Trial / NCT00390000

Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors

NCT00390000

NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Vatalanib and pemetrexed disodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Vatalanib may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving vatalanib together with pemetrexed disodium may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of vatalanib when given together with pemetrexed disodium in treating patients with advanced solid tumors.

Timeline

Start
2007-01-25
Primary completion
2016-08-04
Completion
2016-08-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Pemetrexed Small molecule Intravenous
Subject vatalanib Small molecule Oral