drugset / Trial / NCT00390000
Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Vatalanib and pemetrexed disodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Vatalanib may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving vatalanib together with pemetrexed disodium may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of vatalanib when given together with pemetrexed disodium in treating patients with advanced solid tumors.
Timeline
- Start
- 2007-01-25
- Primary completion
- 2016-08-04
- Completion
- 2016-08-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pemetrexed | Small molecule | — | Intravenous |
| Subject | vatalanib | Small molecule | — | Oral |