drugset / Trial / NCT00390273
Effect of Metformin on Lactate Metabolism
Phase 1/2
Completed
20 enrolled
Centre de Recherche en Nutrition Humaine Rhone-Alpe
Merck Sharp & Dohme LLC · collab
Non-randomizedFactorialOpen-labelTreatment
Summary
The main objective of this study is to evaluate the influence of metformin on lactate metabolism. The main outcome is the lactate production following an exogenous lactate overload in healthy male subjects without metformin and one week later with metformin.
Timeline
- Start
- 2006-12
- Primary completion
- 2007-10
- Completion
- 2007-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | — | — |