drugset / Trial / NCT00398320

Phase II Capecitabine, Oxaliplatin & Bevacizumab for Metastatic / Unresectable Neuroendocrine Tumors

NCT00398320 ↗

Phase 2 Completed 40 enrolled Pamela L. Kunz
NaSingle-groupOpen-labelTreatment

Summary

Given the lack of other viable treatment options for metastatic neuroendocrine tumors, contrasted with our positive anecdotal experience, and the relative tolerability of the treatment regimen for colorectal cancer patients, we propose a single-institution phase II trial investigating the efficacy of capecitabine, oxaliplatin and bevacizumab for patients with metastatic neuroendocrine tumors.

Timeline

Start
2006-11
Primary completion
2012-10
Completion
2012-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 7.5 mg/kg Intravenous
Subject Capecitabine Small molecule 850 mg/m2 Oral
Subject Oxaliplatin Small molecule 130 mg/m2 Intravenous