The Role of Steroids Following Selective Laser Trabeculoplasty

Completed 25 enrolled West Virginia University

RandomizedParallel-groupSingle-blindTreatment

Summary

To evaluate whether or not using topical steroids after selective laser trabeculoplasty affects intraocular pressure outcomes.

Timeline

Start: 2005-09
Primary completion: —
Completion: 2006-06

Outcome

Missed primary endpoint

paper CONCLUSION: A 1-week course of topical prednisolone acetate 1% four times daily did not affect the IOP-lowering effect of selective laser trabeculoplasty in eyes with primary open-angle glaucoma. PMID 20128578 ↗

paper Mean IOP was similar in eyes that did and did not receive steroid therapy at 1 week (17.0 vs 16.3 mm Hg, respectively, P = .613) PMID 20128578 ↗

Publications

Realini T, Charlton J, Hettlinger M. The impact of anti-inflammatory therapy on intraocular pressure reduction following selective laser trabeculoplasty. Ophthalmic Surg Lasers Imaging. 2010 Jan-Feb;41(1):100-3. doi: 10.3928/15428877-20091230-18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Prednisolone	Other / unclassified	1 %	Topical