drugset / Trial / NCT00407290

The Impact of an Epidural Ropivacaine-Neostigmine Injection for Perineal Analgesia at the End of Labor.

NCT00407290

RandomizedParallel-groupOpen-labelTreatment

Summary

Perineal pain after childbirth occurs in the majority of women (with or without episiotomy). Perineal pain can become source of chronic pain in 9%-12% of the cases. Neostigmine a cholinesterase inhibitor at a dose of 500µg combined with Sufentanil or Ropivacaine (=local anaesthetic) is an analgesic. The goal of this study is to examine the effect of the use of epidural Neostigmine for perineal analgesia at the end of the labor on acute pain and on the development of chronic pain post partum.

Timeline

Start
2006-03
Primary completion
Completion
2006-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Neostigmine Other / unclassified 500 ug Other

Indications