Dexmedetomidine for Postoperative Sedation in Patients Undergoing Repair of Thoracoabdominal Aortic Aneurysms

Phase 4 Terminated Massachusetts General Hospital Hospira, now a wholly owned subsidiary of Pfizer · collab

RandomizedSingle-groupDouble-blindTreatment

Summary

The primary objective of this study is to test the hypothesis that time on the ventilator and ICU length of stay will be shorter in TAA patients given postoperative sedation with dexmedetomidine compared to those given standard sedation. Secondary endpoints are: requirement for sedatives vasoactive drugs incidence of postoperative delirium and cost analysis.

Timeline

Start: 2007-01
Primary completion: 2008-01
Completion: 2008-01

Outcome

Outcome not reported

Stopped (Enrollment): “Surgical approach changed therefore subject enrollment not possible.”

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	0.8 ug/kg	—

Indications

No indication recorded.