drugset / Trial / NCT00419536

Safety of LBH589 Alone and in Combination With Intravenous Docetaxel and Prednisone

NCT00419536

Phase 1 Terminated 108 enrolled Novartis Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This 2-arm study is designed to determine the maximum tolerated dose of LBH589 as a single agent and in combination with docetaxel and prednisone 5 mg twice daily (second arm) and to characterize the safety, tolerability, biologic activity and pharmacokinetic profile.

Timeline

Start
2006-05
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Panobinostat Small molecule Oral