Trial of 2nd Generation Anti-CEA Designer T Cells in Gastric Cancer

Summary

This study proposes to determine the safety and tolerability of 2nd generation designer T cells in patients with gastric cancer.Designer T cells are prepared by removing white blood cells from the participant, and then modifying these cells so that they recognize tumor antigen(CEA). These modified cells are then re infused back into the participant so that they can attack and kill tumor cells.Eligibility for this study is diagnosis of carcinoma of the stomach with failure to respond to standard curative therapy. Tumors must express CEA as demonstrated by elevated serum CEA \>10ng/ml and be measurable radiologically or by physical exam.

Timeline

Start

2007-07

Primary completion

2011-04

Completion

2011-04

Drugs

Indications