Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer

Summary

Primary Objective: * To determine the effectiveness of goserelin acetate (Zoladex) in preserving ovarian function in premenopausal women undergoing neoadjuvant and/or adjuvant chemotherapy for primary invasive breast cancer by documenting persistence or resumption of regular menses. Secondary Objectives: * To determine the incidence of pregnancy and the effect for participants' quality of life (QOL) after chemotherapy. * To determine the overall survival and disease-free survival times of study participants.

Timeline

Start

2006-08

Primary completion

2010-07

Completion

2010-07

Drugs

Indications