Study of the Effect of Intramuscular Ephedrine on the Incidence of Nausea and Vomiting During Elective Cesarean Section

Phase 2 Completed 53 enrolled Weill Medical College of Cornell University New York Presbyterian Hospital · collab

RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this research study is to investigate if the incidence of nausea and vomiting that subjects experience during and after a Cesarean section can be reduced by giving a shot of the drug ephedrine into the thigh muscle at the time of spinal anesthesia administration.

Timeline

Start: 2007-02
Primary completion: 2010-09
Completion: 2010-09

Publications

Griffiths JD, Gyte GM, Popham PA, Williams K, Paranjothy S, Broughton HK, Brown HC, Thomas J. Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section. Cochrane Database Syst Rev. 2021 May 18;5(5):CD007579. doi: 10.1002/14651858.CD007579.pub3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ephedrine	Small molecule	25 mg	Intramuscular

Indications

No indication recorded.