drugset / Trial / NCT00433836
Effect of Valsartan Compared to Enalapril on Sitting Systolic Blood Pressure in Children With High Blood Pressure
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this 12-week active controlled trial is to evaluate the safety and efficacy of valsartan 80/160/320 mg (weight stratified) compared with enalapril 10/20/40 mg (weight stratified) on sitting systolic blood pressure (SSBP) in 6 - 17 year old children with hypertension (SSBP ≥ 95th percentile for age gender and height).
Timeline
- Start
- 2007-01
- Primary completion
- 2009-02
- Completion
- 2009-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Enalapril | Other / unclassified | 10 mg | Oral |
| Comparator | Enalapril | Other / unclassified | 20 mg | Oral |
| Comparator | Enalapril | Other / unclassified | 40 mg | Oral |
| Subject | Valsartan | Small molecule | 80 mg | Oral |
| Subject | Valsartan | Small molecule | 160 mg | Oral |
| Subject | Valsartan | Small molecule | 320 mg | Oral |