drugset / Trial / NCT00441155

Patients Completing Core Protocol (CAMN107A2103), Exhibiting Stable Disease (SD), Partial Response (PR) or Complete Response (CR) to Nilotinib in Combination With Imatinib

NCT00441155

Phase 1 Completed 14 enrolled Novartis Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

To provide study drug to patients that benefit from treatment judged by the investigator - to obtain additional long-term safety and efficacy data of this combination regimen in GIST

Timeline

Start
2006-11
Primary completion
2011-01
Completion
2011-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule 0 mg Oral
Subject Imatinib Small molecule 400 mg Oral
Subject Imatinib Small molecule 600 mg Oral
Subject Nilotinib Small molecule 100 mg
Subject Nilotinib Small molecule 200 mg
Subject Nilotinib Small molecule 300 mg
Subject Nilotinib Small molecule 400 mg