drugset / Trial / NCT00442052

To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin

NCT00442052

Phase 1 Completed 80 enrolled POZEN
RandomizedParallel-groupOpen-labelTreatment

Summary

Primary: To compare the gastroprotective effects of a once-daily dose of PA 325 combination tablet combining 325 mg pH sensitive aspirin and 20 mg immediate release omeprazole versus a once-daily dose of 325 mg enteric coated aspirin utilizing Lanza scores from endoscopy findings in normal healthy volunteers.

Timeline

Start
2006-11
Primary completion
Completion
2007-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 325 mg
Subject Omeprazole Other / unclassified 20 mg

Indications

No indication recorded.