Study of MK-0476 in Adult Patients With Acute Asthma (0476-334)

Summary

The study estimates the efficacy and safety of MK0476 and aminophylline intravenous administration in adult participants with acute asthma.

Timeline

Start

2007-03

Primary completion

2007-08

Completion

2007-08

Outcome

Missed primary endpoint

registry analysis (unspecified test); Montelukast 7 mg vs Aminophylline 250 mg; p = 0.871; Difference in LS Means 0.01 (95% CI -0.07 to 0.08); ANCOVA NCT00442338 ↗

registry analysis (unspecified test); Montelukast 14 mg vs Aminophylline 250 mg; p = 0.794; Difference in LS Means -0.01 (95% CI -0.08 to 0.06); ANCOVA NCT00442338 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Aminophylline	Small molecule	250 mg	Intravenous
Subject	Montelukast	Other / unclassified	7 mg	Intravenous
Subject	Montelukast	Other / unclassified	14 mg	Intravenous

Indications