drugset / Trial / NCT00444093
Prospective Randomized Open Label Study of the Treatment of Therapy-associated Diarrhea During Percutaneous Radiation Therapy of the Small Pelvis. - Comparison of Loperamide and Tincture of Opium -
RandomizedParallel-groupOpen-labelTreatment
Summary
Therapy-associated diarrhea during radiation therapy of small pelvis (including enteritis as a result of radiation therapy and enteritis as a result of radiation- and chemotherapy) is a common problem in multimodal cancer therapy. We investigate the therapeutic effect of either loperamide or tinctura opii in therapy- associated diarrhea in patients who receive radiation therapy of the small pelvis with or without chemotherapy.
Timeline
- Start
- 2007-03-05
- Primary completion
- 2008-02-29
- Completion
- 2008-02-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Loperamide | Small molecule | 2 mg | — |
| Subject | opium | Traditional medicine (herbal / TCM) | 5 unknown | — |
| Subject | opium | Traditional medicine (herbal / TCM) | 15 unknown | — |