drugset / Trial / NCT00444093

Prospective Randomized Open Label Study of the Treatment of Therapy-associated Diarrhea During Percutaneous Radiation Therapy of the Small Pelvis. - Comparison of Loperamide and Tincture of Opium -

NCT00444093

RandomizedParallel-groupOpen-labelTreatment

Summary

Therapy-associated diarrhea during radiation therapy of small pelvis (including enteritis as a result of radiation therapy and enteritis as a result of radiation- and chemotherapy) is a common problem in multimodal cancer therapy. We investigate the therapeutic effect of either loperamide or tinctura opii in therapy- associated diarrhea in patients who receive radiation therapy of the small pelvis with or without chemotherapy.

Timeline

Start
2007-03-05
Primary completion
2008-02-29
Completion
2008-02-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Loperamide Small molecule 2 mg
Subject opium Traditional medicine (herbal / TCM) 5 unknown
Subject opium Traditional medicine (herbal / TCM) 15 unknown