drugset / Trial / NCT00444184

24-hour Intraocular Pressure Control With Travoprost/Timolol Fixed Combination Versus Travoprost

NCT00444184

RandomizedCrossoverSingle-blindTreatment

Summary

This 8-week, crossover study will compare the quality of 24-hour IOP control with TTFC versus travoprost when both medications are dosed in the evening. Such a crossover comparison may determine the real efficacy of the new fixed combination versus travoprost monotherapy. The results should enhance the investigators understanding on the best dosing of TTFC and may influence its clinical use in Europe. Finally, the results would better delineate the future role of TTFC in glaucoma management after PG monotherapy, or instead of unfixed therapy with PG analogs and timolol. This study should assist the general ophthalmologist worldwide to plan optimal stepwise medical therapy.

Timeline

Start
2007-03
Primary completion
2008-01
Completion
2008-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Timolol Other / unclassified Other
Comparator Travoprost Other / unclassified Other

Indications