drugset / Trial / NCT00446290

Study of Docetaxel, Capecitabine and Oxaliplatin in Advanced Stomach Cancer

NCT00446290 ↗

Phase 1 Completed 22 enrolled Asan Medical Center
NaSingle-groupOpen-labelTreatment

Summary

Considering synergism between docetaxel (D), capecitabine (X), and oxaliplatin (O) and favourable toxicity profile of oxaliplatin over cisplatin, it is to be expected that combination of docetaxel, capecitabine, and oxaliplatin (DXO) will be more effective than other regimens and feasible in advanced gastric cancer. DXO regimen can be also easily administered on out-patient setting. However, so far, DXO combination has not been tried in advanced gastric cancer. The investigators will determine maximum tolerated dose of DXO regimen in this phase I study.

Timeline

Start
2006-03
Primary completion
2007-10
Completion
2007-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule — —
Subject Docetaxel Small molecule — —
Subject Oxaliplatin Small molecule — —

Indications