Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)

Summary

A study to evaluate the efficacy and safety of sitagliptin in comparison to a commonly used medication in patients with type 2 diabetes

Timeline

Start

2007-03-01

Primary completion

2008-07-25

Completion

2008-07-25

Outcome

Met primary endpoint

paper The between-group difference (95% CI) was 0.14% (0.06, 0.21), thus confirming non-inferiority. PMID 20070351 ↗

Publications

• Results Aschner P, Katzeff HL, Guo H, Sunga S, Williams-Herman D, Kaufman KD, Goldstein BJ; Sitagliptin Study 049 Group. Efficacy and safety of monotherapy of sitagliptin compared with metformin in patients with type 2 diabetes. Diabetes Obes Metab. 2010 Mar;12(3):252-61. doi: 10.1111/j.1463-1326.2009.01187.x. Epub 2009 Nov 25.

Drugs

Indications