drugset / Trial / NCT00455026

Effect of Remifentanil on Electroencephalographic BAR Index During Propofol Anaesthesia

NCT00455026

Phase 1 Completed 45 enrolled Melbourne Health Biopharmica Limited · collab
RandomizedParallel-groupDouble-blindDiagnostic

Summary

Current cortical EEG based depth of anaesthesia monitors do not accurately reflect the effect of opioid drugs. We have developed a new theoretically-based method of analysing the EEG. Our hypothesis is that this new method will more accurately predict depth of anaesthesia than the Bispectral Index (BIS) monitor in patients having elective surgery.

Timeline

Start
2006-03
Primary completion
2007-10
Completion
2007-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Remifentanil Small molecule 0 ng/ml
Comparator Remifentanil Small molecule 2 ng/ml
Comparator Remifentanil Small molecule 4 ng/ml

Indications

No indication recorded.