Role of Exenatide in Type 1 Diabetes

Phase 2 Completed 11 enrolled Montefiore Medical Center National Institutes of Health (NIH) · collab

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to see if giving exenatide and insulin before a meal would lower blood sugars after the meal. This study may help in developing new treatments to help control high blood sugars after meals. This may help improve overall blood sugar control and prevent the long-term effects of diabetes.

Timeline

Start: 2007-03
Primary completion: 2009-03
Completion: 2009-03

Publications

Raman VS, Mason KJ, Rodriguez LM, Hassan K, Yu X, Bomgaars L, Heptulla RA. The role of adjunctive exenatide therapy in pediatric type 1 diabetes. Diabetes Care. 2010 Jun;33(6):1294-6. doi: 10.2337/dc09-1959. Epub 2010 Mar 23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Exenatide	Peptide	1.25 ug	Subcutaneous
Subject	Exenatide	Peptide	2.5 ug	Subcutaneous
Subject	Insulin	Protein / enzyme biologic	—	Subcutaneous

Role of Exenatide in Type 1 Diabetes

Summary

Timeline

Publications

Drugs

Indications