drugset

drugset / Trial / NCT00456599

Study of Gemcitabine and Oxaliplatin With Radiation Therapy in Patients With Pancreatic Cancer

NCT00456599 ↗

Phase 2 Completed 71 enrolled University of Michigan Rogel Cancer Center Johns Hopkins University · collab Ohio State University · collab Princess Margaret Hospital, Canada · collab Sanofi · collab

NaSingle-groupOpen-labelTreatment

Summary

This study will examine a sequence of treatments including pre-operative chemotherapy and radiation, surgery and post-operative chemotherapy for resectable pancreatic cancer.

Timeline

Start: 2007-04
Primary completion: 2012-05
Completion: 2013-01

Publications

Results Kim EJ, Ben-Josef E, Herman JM, Bekaii-Saab T, Dawson LA, Griffith KA, Francis IR, Greenson JK, Simeone DM, Lawrence TS, Laheru D, Wolfgang CL, Williams T, Bloomston M, Moore MJ, Wei A, Zalupski MM. A multi-institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer. Cancer. 2013 Aug 1;119(15):2692-700. doi: 10.1002/cncr.28117. Epub 2013 May 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gemcitabine	Small molecule	1000 mg/m2	—
Subject	Oxaliplatin	Small molecule	85 mg/m2	—

Indications