drugset / Trial / NCT00457457
Study the Effects of Different Doses of UK-369,003 in Men With Lower Urinary Tract Symptoms.
RandomizedParallel-groupTriple-blindTreatment
Summary
This is a 12 week study in which different doses and formulations of UK-369,003 will be administered to patients with a diagnosis of enlarged prostate. Patients will complete a series of questionnaires before, during and after treatment to assess if UK-369,003 has improved their urinary symptoms and erectile function . There will be several blood samples taken during the study to asses the level of drug in the blood and correlate it with the responses to the questionnaires.
Timeline
- Start
- 2007-05
- Primary completion
- 2008-04
- Completion
- 2008-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GISADENAFIL | Small molecule | 10 mg | — |
| Subject | GISADENAFIL | Small molecule | 25 mg | — |
| Subject | GISADENAFIL | Small molecule | 40 mg | — |
| Subject | GISADENAFIL | Small molecule | 50 mg | — |
| Subject | GISADENAFIL | Small molecule | 100 mg | — |
| Comparator | Tamsulosin | Other / unclassified | 0.4 mg | — |