drugset / Trial / NCT00459810
Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer
Phase 2
Terminated
21 enrolled
OHSU Knight Cancer Institute
National Cancer Institute (NCI) · collab
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy, such as paclitaxel poliglumex, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Estradiol may kill prostate cancer cells that no longer respond to hormone therapy. Giving paclitaxel poliglumex together with estradiol may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving paclitaxel poliglumex together with estradiol works in treating patients with stage IV prostate cancer.
Timeline
- Start
- 2007-02
- Primary completion
- 2009-07
- Completion
- 2009-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Estradiol | Other / unclassified | 0.2 mg | Other |
| Subject | paclitaxel poliglumex | Other / unclassified | 150 mg/m2 | Intravenous |