drugset / Trial / NCT00462020
Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis
RandomizedParallel-groupOpen-labelTreatment
Summary
The objective of this study is to scientifically evaluate two different management strategies for perforated appendicitis. The hypothesis is that early discharge with oral antibiotic therapy may result in a dramatic decrease in medical care expenses for the patient. The primary outcome variable between the two strategies is abscess rate.
Timeline
- Start
- 2007-03
- Primary completion
- 2008-11
- Completion
- 2008-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ampicillin | Unknown | — | Oral |
| Subject | clavulanic acid | Small molecule | — | Oral |
| Comparator | Ceftriaxone | Other / unclassified | 50 mg/kg | Intravenous |
| Comparator | Metronidazole | Small molecule | 30 mg/kg | Intravenous |