Ceftriaxone
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | ROCEPHIN KIT | — | 1984-12-21 | fda.gov ↗ |
Trials 86 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT04977882 | Oct 2020 → Aug 2022 | colon carcinoma | University of Rome Tor Vergata | Completed | No outcome recorded |
| Phase 13 trials | ||||||
| Phase 1 | NCT03895567 | Dec 2026 | — | University of Oxford | Suspended | No outcome recorded |
| Phase 1 | NCT05724628 | Oct → Nov 2023 | appendicitis | University of Texas Southwestern Medical Center | Withdrawn | No outcome recorded |
| Phase 1 | NCT00493220 | Jun → Sep 2007 | — | Baxter Healthcare Corporation | Completed | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT06785402 | May 2026 | post-treatment Lyme disease syndrome | Hackensack Meridian Health | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT02473640 | Jun 2015 → Apr 2016 | — | Theriva Biologics, Inc. | Completed | No outcome recorded |
| Phase 1/2 | NCT02419001 | Mar → Sep 2015 | — | Theriva Biologics, Inc. | Completed | No outcome recorded |
| Phase 1/2 | NCT00591318 | Oct 2007 → Mar 2011 | schizoaffective disorder, schizophrenia | Research Foundation for Mental Hygiene, Inc. | Terminated | No outcome recorded |
| Phase 214 trials | ||||||
| Phase 2 | NCT07485010 | Apr 2027 → Apr 2031 expected | pulmonary non-tuberculous mycobacterial infection | The University of Queensland | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06406114 | May 2025 → Jul 2028 expected | anaphylaxis, drug allergy, drug pseudoallergy | Massachusetts General Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT05470517 | Jan 2023 → Feb 2024 | appendicitis | Johns Hopkins All Children's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT05375240 | Jun 2022 → Jun 2024 | ischemic stroke | Tianjin Medical University General Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT05149287 | Dec 2021 → Apr 2022 | articular cartilage disorder | Austin V Stone | Terminated | No outcome recorded |
| Phase 2 | NCT04999592 | Aug 2021 → Mar 2024 | cardiac arrest, pneumonia | David J. Gagnon | Terminated | No outcome recorded |
| Phase 2 | NCT05216744 | Jul 2021 → Feb 2022 | chlamydia trachomatis infectious disease, gonorrhea | Haiphong University of Medicine and Pharmacy | Completed | No outcome recorded |
| Phase 2 | NCT03794765 | Apr 2019 → Mar 2020 | ulcerative colitis | Post Graduate Institute of Medical Education and Research, Chandigarh | Completed | No outcome recorded |
| Phase 2 | NCT03413384 | Feb 2019 → Jul 2025 overdue | Parkinson disease | BrainX Corporation | Active not recruiting | No outcome recorded |
| Phase 2 | NCT03681431 | Apr 2018 → Apr 2019 | infective endocarditis | Andalusian Public Foundation for Health Research in Seville | Completed | No outcome recorded |
| Phase 2 | NCT02746276 | Apr → Sep 2016 | protein-energy malnutrition | University of Oxford | Unknown | No outcome recorded |
| Phase 2 | NCT00512616 | Aug 2007 → Sep 2009 | bipolar disorder | National Institute of Mental Health (NIMH) | Withdrawn | No outcome recorded |
| Phase 2 | NCT00451386 | Jan 2002 → Dec 2003 | bacterial pneumonia, urinary tract infection | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 2 | NCT00037479 | Dec 1999 → ? | Lyme disease | National Institute of Neurological Disorders and Stroke (NINDS) | Completed | No outcome recorded |
| Phase 2/33 trials | ||||||
| Phase 2/3 | NCT06527989 | Sep 2024 → Sep 2025 overdue | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT05051163 | Jun 2021 → Jun 2024 | HIV infectious disease, protein-energy malnutrition | Makerere University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02561442 | Oct → Dec 2015 | — | scPharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 318 trials | ||||||
| Phase 3 | NCT06572761 | Sep 2026 → May 2030 expected | cervical incompetence | Assistance Publique - Hôpitaux de Paris | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07710118 | Jul 2026 → Dec 2028 expected | gonorrhea | National Taiwan University Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT05821478 | May 2025 → Feb 2027 expected | hidradenitis suppurativa | Institut Pasteur | Recruiting | No outcome recorded |
| Phase 3 | NCT05654896 | Nov 2022 → Nov 2023 | — | Nadeem Iqbal | Unknown | No outcome recorded |
| Phase 3 | NCT04041791 | Aug 2019 → Apr 2024 | pneumonia | University of Oxford | Completed | No outcome recorded |
| Phase 3 | NCT03174236 | Sep 2017 → Jan 2020 | poisoning, protein-energy malnutrition | University of Oxford | Unknown | No outcome recorded |
| Phase 3 | NCT02389036 | May 2017 → Apr 2023 | critical illness polyneuropathy, infectious disease with sepsis | The George Institute | Completed | No outcome recorded |
| Phase 3 | NCT02795949 | Oct 2016 → Jan 2020 | bacterial infectious disease | Andalusian Public Foundation for Health Research in Seville | Completed | No outcome recorded |
| Phase 3 | NCT02735707 | Apr 2016 → Feb 2026 overdue | pneumonia | UMC Utrecht | Recruiting | No outcome recorded |
| Phase 3 | NCT02265406 | Oct 2015 → Jul 2020 | — | Poitiers University Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02142751 | Jul 2014 → Dec 2018 | escherichia coli infection | Andalusian Public Foundation for Health Research in Seville | Completed | No outcome recorded |
| Phase 3 | NCT03477422 | Jan 2014 → May 2017 | acute pyelonephritis | Venus Remedies Limited | Completed | No outcome recorded |
| Phase 3 | NCT02177994 | Sep 2013 → Aug 2014 | puerperal infection | Ain Shams Maternity Hospital | Completed | No outcome recorded |
| Phase 3 | NCT01473836 | Nov 2011 → Oct 2012 | infectious peritonitis | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT00372541 | Sep 2006 → Mar 2007 | pneumonia | Makerere University | Completed | No outcome recorded |
| Phase 3 | NCT00189384 | Nov 2003 → Dec 2005 | bacterial infectious disease with sepsis | Aga Khan University | Unknown | No outcome recorded |
| Phase 3 | NCT00481702 | Dec 2001 → Jun 2003 | intestinal infectious disease | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT00161330 | Jun 2000 → Jul 2005 | urinary tract infection | University of Padova | Terminated | No outcome recorded |
| Phase 431 trials | ||||||
| Phase 4 | NCT07484633 | Apr 2026 → Apr 2028 expected | infectious disease with sepsis | Semmelweis University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06766461 | Jan 2025 → Dec 2026 expected | infectious disease with sepsis | Erasmus Medical Center | Recruiting | No outcome recorded |
| Phase 4 | NCT06423898 | Oct 2024 → Jul 2027 expected | infective endocarditis | Andalusian Public Foundation for Health Research in Seville | Recruiting | No outcome recorded |
| Phase 4 | NCT06494072 | Aug 2024 → May 2028 expected | — | Medical College of Wisconsin | Recruiting | No outcome recorded |
| Phase 4 | NCT06349122 | Aug 2024 → Mar 2027 expected | bacterial vaginosis | Assistance Publique Hopitaux De Marseille | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06396078 | Jul 2024 → Dec 2026 expected | preterm premature rupture of the membranes | Ohio State University | Recruiting | No outcome recorded |
| Phase 4 | NCT06220929 | Jan → Dec 2024 | infectious disease with sepsis, liver disorder | Sichuan Provincial People's Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05156437 | Mar 2022 → Oct 2024 | endocarditis | West Virginia University | Terminated | No outcome recorded |
| Phase 4 | NCT05079620 | Nov 2021 → Apr 2024 | aspiration pneumonia, aspiration pneumonitis | UConn Health | Terminated | No outcome recorded |
| Phase 4 | NCT04975945 | Aug → Dec 2021 | — | The Grant Medical College & Sir J.J. Group of Hospitals | Withdrawn | No outcome recorded |
| Phase 4 | NCT04218695 | Aug 2020 → May 2021 | cirrhosis of liver | Beth Israel Deaconess Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT04056806 | Aug 2019 → Jun 2022 | esophageal varices with bleeding | E-DA Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03675178 | Sep 2018 → Jun 2019 | pneumonia | China Academy of Chinese Medical Sciences | Unknown | No outcome recorded |
| Phase 4 | NCT03012360 | Feb 2018 → Jul 2024 | — | University Hospital, Lille | Terminated | No outcome recorded |
| Phase 4 | NCT03179384 | Jun 2017 → Feb 2019 | acute pyelonephritis | Centre Hospitalier Universitaire de Nice | Completed | No outcome recorded |
| Phase 4 | NCT02736682 | Sep 2015 → Feb 2016 | puerperal infection | Makerere University | Completed | No outcome recorded |
| Phase 4 | NCT04202068 | Jul 2015 → May 2016 | gonorrhea | Xiangbei Welman Pharmaceutical Co., Ltd | Completed | No outcome recorded |
| Phase 4 | NCT04066621 | Apr 2015 → Jun 2016 | bacterial urinary tract infection, respiratory tract infectious disorder | Xiangbei Welman Pharmaceutical Co., Ltd | Completed | No outcome recorded |
| Phase 4 | NCT02224040 | Aug 2013 → Dec 2014 | typhoid fever | Sheba Medical Center | Unknown | No outcome recorded |
| Phase 4 | NCT01745679 | Dec 2012 → Dec 2015 | infectious disorder of the nervous system, meningitis | Nantes University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01390623 | Jul 2011 → Jul 2013 | acute pyelonephritis | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 4 | NCT01278017 | Aug 2010 → Jun 2011 | diarrheal disease | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01247909 | Apr 2010 → Feb 2015 | bacterial meningitis | Kamuzu University of Health Sciences | Completed | No outcome recorded |
| Phase 4 | NCT01678365 | Jul 2008 → Oct 2009 | appendicitis | HaEmek Medical Center, Israel | Completed | No outcome recorded |
| Phase 4 | NCT01265173 | Apr 2007 → Jun 2018 | cirrhosis of liver | Korea University | Completed | No outcome recorded |
| Phase 4 | NCT00449800 | Jul 2006 → Mar 2007 | infectious disease with sepsis | Association Pour La Promotion A Tours De La Reanimation Medicale | Unknown | No outcome recorded |
| Phase 4 | NCT00429975 | Aug 2004 → Sep 2005 | streptococcal pneumonia | Hospital Mutua de Terrassa | Terminated | No outcome recorded |
| Phase 4 | NCT00157898 | Jan → Aug 2004 | — | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 4 | NCT00035347 | Jan 2001 → Jun 2002 | pneumonia | Pfizer | Completed | No outcome recorded |
| Phase 4 | NCT00374959 | Oct 2000 → Oct 2003 | pneumonia | Hospital Universitario Principe de Asturias | Completed | No outcome recorded |
| Phase 4 | NCT01559753 | Jan 1998 → Sep 2002 | — | Centre Hospitalier Universitaire de Besancon | Completed | No outcome recorded |
| Phase not applicable12 trials | ||||||
| — | NCT07030673 | Feb 2025 → Mar 2027 expected | viral infectious disease | Centre Hospitalier Universitaire, Amiens | Recruiting | No outcome recorded |
| — | NCT06532409 | Oct 2024 → Sep 2025 overdue | pneumonia | RESnTEC, Institute of Research | Not yet recruiting | No outcome recorded |
| — | NCT07308457 | Sep 2024 → Jun 2027 expected | infectious disease | Pomeranian Medical University Szczecin | Recruiting | No outcome recorded |
| — | NCT05750966 | Jul 2023 → Apr 2026 | cholangitis | Academic Medical Center - University of Amsterdam | Completed | No outcome recorded |
| — | NCT04839653 | May 2021 → Apr 2022 | acute respiratory distress syndrome, bacterial infectious disease, infectious disease with sepsis, pneumonia | MEDSI Clinical Hospital 1, ICU | Unknown | No outcome recorded |
| — | NCT04935515 | Apr → May 2021 | COVID-19 | Manimarane Arjunan, MD,DM (Cardiology) | Completed | No outcome recorded |
| — | NCT03518463 | Jun → Jul 2017 | pregnancy disorder | Mbarara University of Science and Technology | Completed | No outcome recorded |
| — | NCT02996656 | Dec 2016 → Dec 2026 expected | bacterial infectious disease | University of Montreal | Recruiting | No outcome recorded |
| — | NCT02334124 | Jan 2015 → Jun 2017 | cellulitis | Murdoch Childrens Research Institute | Completed | No outcome recorded |
| — | NCT01988428 | Jun 2014 → Jun 2017 | infectious disease with sepsis | Amsterdam UMC, location VUmc | Completed | No outcome recorded |
| — | NCT00000648 | ? → Feb 1996 | HIV infectious disease, neurosyphilis | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| — | NCT00002052 | — | HIV infectious disease, salmonellosis | University of Southern California | Completed | No outcome recorded |
Also used as a comparator or background therapy in 104 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 04 trials | ||||||
| Phase 0 | NCT06611111 Comparator | Feb 2025 → Dec 2026 expected | post-treatment Lyme disease syndrome | State University of New York - Upstate Medical University | Recruiting | No outcome recorded |
| Phase 0 | NCT05761405 Comparator | Jan 2024 → Oct 2025 | urinary tract infection | Centre Hospitalier Universitaire Vaudois | Unknown | No outcome recorded |
| Phase 0 | NCT05849090 Comparator | Mar 2023 → Dec 2024 | infectious disease | University of Utah | Completed | No outcome recorded |
| Phase 0 | NCT02099240 Comparator | Mar 2014 → Nov 2018 | osteomyelitis | University of Louisville | Terminated | No outcome recorded |
| Phase 14 trials | ||||||
| Phase 1 | NCT06616168 Background | Sep 2023 → Aug 2026 overdue | bacterial vaginosis | Danylo Halytsky Lviv National Medical University | Active not recruiting | No outcome recorded |
| Phase 1 | NCT03840811 Background | Apr 2017 → Nov 2019 | gonorrhea | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1 | NCT04870138 Background | Mar 2013 → Apr 2015 | gonorrhea | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1 | NCT00004216 Background | Aug 1999 → Jan 2008 | cancer of unknown primary site | Vion Pharmaceuticals | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT04461925 Background | May 2020 → May 2021 | pneumonia | Institute of Cell Therapy | Unknown | No outcome recorded |
| Phase 213 trials | ||||||
| Phase 2 | NCT07318584 Comparator | Mar 2026 → Feb 2028 expected | escherichia coli discitis | Oregon Health and Science University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT05943223 Comparator | Sep 2024 → Jul 2025 | appendicitis | McMaster Children's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT05121974 Comparator | Aug 2022 → Mar 2025 overdue | shigellosis | International Centre for Diarrhoeal Disease Research, Bangladesh | Active not recruiting | No outcome recorded |
| Phase 2 | NCT05294588 Background | Apr 2022 → Feb 2026 | gonorrhea | University of North Carolina, Chapel Hill | Completed | No outcome recorded |
| Phase 2 | NCT05398081 Comparator | Dec 2021 → Feb 2022 | — | Dr. Promise Tamunoipiriala Jaja | Completed | No outcome recorded |
| Phase 2 | NCT02742948 Comparator | Apr → Aug 2016 | endometritis | Cairo University | Unknown | No outcome recorded |
| Phase 2 | NCT02257918 Comparator | Nov 2014 → Dec 2015 | gonorrhea | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 2 | NCT02098486 Comparator | Mar 2014 → Sep 2015 | cholangitis | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01756924 Comparator | Dec 2012 → Jul 2014 | periprosthetic joint infection | Arrevus Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT01757236 Background | Oct 2012 → Apr 2016 | periprosthetic joint infection | University Hospital, Tours | Unknown | No outcome recorded |
| Phase 2 | NCT01160640 Comparator | Nov 2010 → Aug 2015 | pelvic inflammatory disease | Harold Wiesenfeld | Completed | No outcome recorded |
| Phase 2 | NCT00797108 Comparator | Jan → Jun 2009 | bacterial pneumonia | Pfizer | Completed | No outcome recorded |
| Phase 2 | NCT00111644 Comparator | Mar 2005 → Jan 2007 | bacterial pneumonia | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT07229755 Background | Jul → Dec 2024 | urinary tract infection | Ain Shams University | Completed | No outcome recorded |
| Phase 2/3 | NCT05293132 Background | Feb 2022 → Jun 2023 | infectious disease with sepsis | Ain Shams University | Completed | No outcome recorded |
| Phase 2/3 | NCT04879030 Background | Jan → Aug 2020 | chronic obstructive pulmonary disease | Haiphong University of Medicine and Pharmacy | Completed | No outcome recorded |
| Phase 2/3 | NCT02605122 Comparator | Apr 2016 → Mar 2018 | bacterial pneumonia | Melinta Therapeutics, Inc. | Terminated | No outcome recorded |
| Phase 2/3 | NCT01530763 Comparator | Sep 2012 → Apr 2014 | infectious disease | Forest Laboratories | Completed | No outcome recorded |
| Phase 331 trials | ||||||
| Phase 3 | NCT07332325 Background | Oct 2026 → Mar 2029 expected | infectious disease with sepsis, tuberculosis | University of Virginia | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07631364 Comparator | Sep 2026 → Oct 2028 expected | gonorrhea | Assistance Publique - Hôpitaux de Paris | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06819592 Comparator | Oct 2025 → Aug 2029 expected | brain injury, intellectual disability | The George Institute | Recruiting | No outcome recorded |
| Phase 3 | NCT06847126 Comparator | Feb 2025 → Jun 2026 overdue | liver abscess (disease) | Post Graduate Institute of Medical Education and Research, Chandigarh | Recruiting | No outcome recorded |
| Phase 3 | NCT05971550 Comparator | Sep 2023 → Dec 2025 | gonorrhea | Assistance Publique - Hôpitaux de Paris | Unknown | No outcome recorded |
| Phase 3 | NCT05074147 Background | May 2022 → Nov 2024 | osteomyelitis | Tourcoing Hospital | Withdrawn | No outcome recorded |
| Phase 3 | NCT05417997 Background | May → Dec 2021 | COVID-19, bacterial pneumonia, influenza | RAAS Nutritionals, LLC | Completed | No outcome recorded |
| Phase 3 | NCT03959527 Comparator | Nov 2019 → Aug 2023 | gonorrhea | Global Antibiotics Research and Development Partnership | Completed | No outcome recorded |
| Phase 3 | NCT04010539 Comparator | Oct 2019 → Oct 2023 | gonorrhea | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 3 | NCT03688295 Comparator | Feb 2019 → Sep 2025 overdue | appendicitis | Centre Hospitalier Universitaire, Amiens | Recruiting | No outcome recorded |
| Phase 3 | NCT03439124 Comparator | Nov 2017 → Mar 2020 | bacterial pneumonia | Basilea Pharmaceutica | Completed | No outcome recorded |
| Phase 3 | NCT03294395 Comparator | Sep 2017 → Jun 2020 | gonorrhea | Public Health Service of Amsterdam | Completed | No outcome recorded |
| Phase 3 | NCT02473263 Comparator | May 2016 → Feb 2019 | — | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT02659033 Comparator | Mar 2016 | — | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT02424461 Comparator | Jan 2015 → Feb 2019 | urinary tract infection | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT02443285 Comparator | Jan 2015 → Dec 2019 | infectious peritonitis | Tanta University | Unknown | No outcome recorded |
| Phase 3 | NCT02210325 Comparator | Aug 2014 → Feb 2017 | gonorrhea | Melinta Therapeutics, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT02015637 Comparator | Jan → Nov 2014 | gonorrhea | Melinta Therapeutics, Inc. | Terminated | No outcome recorded |
| Phase 3 | NCT01371838 Comparator | Dec 2011 → May 2013 | bacterial pneumonia | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT01602874 Comparator | Jan 2011 → May 2014 | bacterial pneumonia | Pfizer | Withdrawn | No outcome recorded |
| Phase 3 | NCT00914888 Comparator | Jan 2011 → May 2014 | bacterial pneumonia | Wyeth is now a wholly owned subsidiary of Pfizer | Withdrawn | No outcome recorded |
| Phase 3 | NCT01254344 Comparator | Dec 2010 → Dec 2011 | infectious disease | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT01014013 Comparator | Apr 2008 → Feb 2009 | urinary tract infection | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT00717561 Comparator | Feb 2008 → May 2009 | pneumonia | Bayer | Completed | No outcome recorded |
| Phase 3 | NCT00621504 Comparator | Jan → Dec 2008 | bacterial pneumonia | Forest Laboratories | Completed | No outcome recorded |
| Phase 3 | NCT00509106 Comparator | Jul 2007 → Aug 2008 | bacterial pneumonia | Forest Laboratories | Completed | No outcome recorded |
| Phase 3 | NCT00349622 Comparator | Jul 2006 → Nov 2012 | amyotrophic lateral sclerosis | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT00326287 Comparator | Jun 2006 → Jul 2007 | pneumonia | Basilea Pharmaceutica | Completed | No outcome recorded |
| Phase 3 | NCT00769171 Comparator | Oct 2005 → Dec 2006 | infectious peritonitis | Bayer | Completed | No outcome recorded |
| Phase 3 | NCT00138801 Comparator | Mar 2004 → Mar 2008 | Lyme disease | Sorlandet Hospital HF | Completed | No outcome recorded |
| Phase 3 | NCT00431678 Comparator | Jan 2004 → Jul 2005 | pneumonia | Bayer | Completed | No outcome recorded |
| Phase 428 trials | ||||||
| Phase 4 | NCT07537413 Comparator | Sep 2026 → Aug 2027 expected | pneumonia | University of Maryland, Baltimore | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07236944 Comparator | Dec 2025 → Mar 2029 expected | bacterial urinary tract infection | Uppsala University | Recruiting | No outcome recorded |
| Phase 4 | NCT05544565 Background | Mar 2023 → Jan 2028 expected | acute pyelonephritis | Assistance Publique - Hôpitaux de Paris | Recruiting | No outcome recorded |
| Phase 4 | NCT05980871 Comparator | Mar 2023 → Jul 2025 | syphilis | National Taiwan University Hospital | Terminated | No outcome recorded |
| Phase 4 | NCT05199324 Comparator | Jun 2022 → May 2026 overdue | gram-negative bacterial infections | Tan Tock Seng Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT05027516 Comparator | Jan → May 2022 | gonorrhea | Institute of Tropical Medicine, Belgium | Completed | No outcome recorded |
| Phase 4 | NCT06090565 Comparator | Apr 2021 → Jun 2022 | gonorrhea | Bulovka Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04563325 Comparator | Sep 2020 → Jan 2024 | bacterial infectious disease, infective arthritis, osteomyelitis | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase 4 | NCT03068741 Comparator | Mar 2020 → Nov 2025 | infectious disease with sepsis | Dr. Damon Scales | Completed | No outcome recorded |
| Phase 4 | NCT04141787 Comparator | Jul 2019 → Jul 2023 | abscess, bacterial arthritis, infectious disorder of the nervous system, osteomyelitis +1 | Vancouver Island Health Authority | Unknown | No outcome recorded |
| Phase 4 | NCT03560232 Comparator | Jul 2018 → Feb 2020 | — | Mercy Health Ohio | Terminated | No outcome recorded |
| Phase 4 | NCT03922919 Comparator | Apr 2018 → Apr 2020 | bacterial infectious disease | Centre Hospitalier Universitaire de Besancon | Unknown | No outcome recorded |
| Phase 4 | NCT03087656 Comparator | Mar 2017 → Feb 2024 | cholangitis | University of Southern California | Unknown | No outcome recorded |
| Phase 4 | NCT02384200 Background | Mar 2015 → Feb 2017 | nephrolithiasis, urinary tract infection | University of California, San Diego | Completed | No outcome recorded |
| Phase 4 | NCT01723150 Comparator | Nov 2013 → Jan 2018 | liver abscess (disease) | National University Hospital, Singapore | Completed | No outcome recorded |
| Phase 4 | NCT01669980 Comparator | Oct 2012 → May 2014 | pneumonia | Forest Laboratories | Completed | No outcome recorded |
| Phase 4 | NCT01645735 Comparator | Oct 2012 → Dec 2013 | respiratory tract infectious disorder | Forest Laboratories | Completed | No outcome recorded |
| Phase 4 | NCT01659866 Comparator | Aug 2012 → Aug 2015 | infectious disease | Northwestern University | Completed | No outcome recorded |
| Phase 4 | NCT01635530 Comparator | Aug 2012 → Dec 2017 | Lyme disease | Turku University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01421693 Comparator | Sep 2011 → Jul 2014 | typhoid fever | Oxford University Clinical Research Unit, Vietnam | Completed | No outcome recorded |
| Phase 4 | NCT01207739 Comparator | Sep 2010 → Oct 2013 | Borrelia infectious disease, Lyme disease | Radboud University Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00895089 Comparator | May 2009 → Dec 2010 | liver abscess (disease) | Kaohsiung Veterans General Hospital. | Completed | No outcome recorded |
| Phase 4 | NCT02123628 Comparator | Jun 2007 → Jun 2010 | diabetes mellitus | Tourcoing Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00230971 Comparator | Oct 2005 → Sep 2008 | abscess, appendicitis, cholecystitis, diverticulitis +2 | Wyeth is now a wholly owned subsidiary of Pfizer | Completed | No outcome recorded |
| Phase 4 | NCT00195351 Comparator | Sep 2005 → Feb 2008 | appendicitis, cholecystitis, diverticulitis, nosocomial infection +1 | Wyeth is now a wholly owned subsidiary of Pfizer | Completed | No outcome recorded |
| Phase 4 | NCT00136656 Comparator | Jul 2005 → Jun 2008 | pyelonephritis | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 4 | NCT01166932 Comparator | Apr 2005 → Apr 2007 | pneumonia | UPECLIN HC FM Botucatu Unesp | Completed | No outcome recorded |
| Phase 4 | NCT00358202 Comparator | Mar 2002 → Apr 2006 | pneumonia | CPL Associates | Completed | No outcome recorded |
| Phase not applicable18 trials | ||||||
| — | NCT07552870 Comparator | Jan → Apr 2026 | cirrhosis of liver | Shahida Islam Medical Complex | Completed | No outcome recorded |
| — | NCT07148622 Comparator | Oct 2024 → Aug 2025 | preterm premature rupture of the membranes | Yuzuncu Yil University | Completed | No outcome recorded |
| — | NCT06437964 Comparator | May 2024 → Jan 2026 | cirrhosis of liver, esophageal varices with bleeding, portal hypertension | Second Affiliated Hospital, School of Medicine, Zhejiang University | Completed | No outcome recorded |
| — | NCT06080698 Comparator | Feb 2024 → May 2027 expected | gram-negative bacterial infections | Johns Hopkins University | Recruiting | No outcome recorded |
| — | NCT06166381 Background | Jan → Dec 2024 overdue | bacterial infectious disease | University of Duhok | Recruiting | No outcome recorded |
| — | NCT06454643 Comparator | Jan 2020 → Jan 2021 | — | Al-Rasheed University College | Completed | No outcome recorded |
| — | NCT03657836 Background | Aug 2018 → Jan 2019 | bronchitis | Nazarbayev University Medical Center | Completed | No outcome recorded |
| — | NCT02800785 Comparator | May 2016 → Mar 2020 | appendicitis | University of Washington | Completed | No outcome recorded |
| — | NCT02567825 Background | Nov 2015 → Mar 2020 | otitis media | Alejandro Hoberman | Completed | No outcome recorded |
| — | NCT02515565 Background | Sep 2015 → Apr 2018 | pneumonia | University of Granada | Unknown | No outcome recorded |
| — | NCT03449940 Comparator | Jan 2015 → Jan 2017 | erectile dysfunction | Ministry of Health, Jamaica | Completed | No outcome recorded |
| — | NCT03061604 Background | Nov 2014 → Nov 2017 | varicose disease | Theodor Bilharz Research Institute | Completed | No outcome recorded |
| — | NCT01163994 Comparator | Jun 2010 → Oct 2017 | — | University Medical Centre Ljubljana | Unknown | No outcome recorded |
| — | NCT00942006 Comparator | Jul 2009 → Nov 2010 | — | University Medical Centre Ljubljana | Unknown | No outcome recorded |
| — | NCT00910533 Comparator | Jan 2009 → Dec 2018 | Lyme disease | University Medical Centre Ljubljana | Unknown | No outcome recorded |
| — | NCT00566111 Comparator | Sep 2007 → Dec 2009 | bipolar depression | Yale University | Terminated | No outcome recorded |
| — | NCT00644150 Background | Apr 2007 → Jul 2011 | HIV infectious disease, chlamydia infectious disease, gonorrhea | University of California, Los Angeles | Completed | No outcome recorded |
| — | NCT00462020 Comparator | Mar 2007 → Nov 2008 | appendicitis | Children's Mercy Hospital Kansas City | Completed | No outcome recorded |
Evidence & citations 27 cited values
Every value below carries the sentence it was read from. 197 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ceftriaxone | “Patients not already receiving a therapeutic antibiotic will be prescribed cefotaxime 1g six-hourly or ceftriaxone 1g daily, with dose adjusted as appropriate for organ...” NCT02389036 ↗182“Beta lactam antibiotics for non-ESBL E. coli infections include preferred ceftriaxone or alternative cephalosporins (cefepime, ceftazidime), penicillins...” NCT07318584 ↗ “Second- or third-generation cephalosporin (cefuroxime, cefotaxime, or ceftriaxone) with or without erythromycin, given parenterally; parenteral therapy should continue until...” NCT02515565 ↗ “The intravenous-group will receive Beta-lactam antimicrobials (i.e Piperacillin-Tazobactum 4.5g q 8 hourly or Ceftriaxone 1g q 12 hourly or Meropenem 1g q 8 hourly or...” NCT06847126 ↗ “empiric initiation of the enhanced spectrum antimicrobial therapy regimen (rifampin, isoniazid, linezolid, and levofloxacin) for 14 days plus standard care which includes...” NCT07332325 ↗ “The beta-lactam antibiotics with activity against gram-negative bacilli in this study included piperacillin-tazobactam, ticarcillin-clavulanate, imipenem-cilastin, meropenem,...” NCT04879030 ↗ “Ceftriaxone infusion. Ceftriaxone is a beta-lactam antibiotic that is the standard-of-care antibiotic for prophylaxis of asymptomatic bacteriuria in Switzerland.” NCT05761405 ↗ “Commonly used intravenous antibiotics (and doses) for treatment of Gram-negative bacteraemia include ceftriaxone 2 g daily or cefazolin 2 g three times daily.” NCT05199324 ↗ “Ceftriaxone (50 mg/kg once a day by intravenous/intramuscular route) AND/OR Amikacin (20 mg/kg once a day by intravenous/intramuscular route) during 3 days.” NCT05544565 ↗ “standard to double dosing of beta-lactam antibiotics (cefuroxime, ceftazidime, ceftriaxone, cefotaxime, amoxicillin, amoxicillin/clavulanic acid,” PMID 40119275 ↗ Mar 2025 “Parenteral antibiotic (ceftriaxone) 1 g to be given in 3 doses, at induction of anesthesia, 12 hours postoperative, and 24 hours postoperative.” NCT06166381 ↗ “Single dose arm receive 2g of IV Ceftriaxone and 500 mgs ofIntra venous Metronidazole given to the mothers 30-60 minutes pre operative.” NCT02736682 ↗ “These include intravenous ceftriaxone, ampicillin, and amoxicillin and oral amoxicillin and amoxicillin-clavulanic acid.” NCT02605122 ↗ “Patients will be given standard therapy antibiotics cefuroxime and ceftriaxone for up to 7 days period.” NCT03657836 ↗ “to receive intravenous ceftriaxone 2 g or placebo once within the 12 h following tracheal intubation.” PMID 38262428 ↗ Jan 2024 “Intravenous ceftriaxone with either oral methyl prednisolone or intravenous dexamethasone was given” NCT04935515 ↗ “Drugs used would be anything from: zosyn, ciprofloxacin or ceftriaxone and flagyl, augmentin” NCT05724628 ↗ “Includes antibiotics such as ceftriaxone, cefepime, piperacillin-tazobactam, and meropenem.” NCT06080698 ↗ “Single dose of Rocephine® (= ceftriaxone 1g + lidocaine 35mg) intramuscular injection” NCT05027516 ↗ “Ceftriaxone was used as standard-of-care cephalosporin for the treatment of CAP.” NCT03439124 ↗ “Ceftriaxone 2 gr and Metronidazole 1.5 gr per day for 2 days postoperatively” NCT04977882 ↗ “After open-label i.v. ceftriaxone 2000 mg qd via a peripheral i.v. catheter” NCT01207739 ↗ “a 3-week course of ceftriaxone (Rocephin) IV injection (daily dose 2g/day)” NCT05821478 ↗ “or intravenous ceftriaxone for 4 days followed by oral cefixime for 6 days” PMID 22291112 ↗ Jan 2012 “cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside” NCT01602874 ↗ “2 g ceftriaxone by intravenous injection every 24 h up to the operation” PMID 32487213 ↗ Jun 2020 “Ceftriaxone 1gm intravenously dose of ceftriaxone 1gm at 24 h interval” NCT04056806 ↗ “ceftriaxone 2gm/24 hour or meropenem 1g/8 hours, linezolid 600/12hours” NCT05293132 ↗ “Period 1: Ceftriaxone 1 g infused IV over 30 minutes only, no SYN-004” NCT02419001 ↗ “cephalosporins; cefotaxime, cefuroxime, ceftriaxone, 3) carbapenems” NCT07236944 ↗ “Intravenous infusion of 2.0g ceftriaxone before endoscopic therapy” NCT06437964 ↗ “* Ceftriaxone IV,intramuscularly or subcutaneously 2g once daily” NCT02123628 ↗ “Ampicillin 12g/24h plus ceftriaxone 4g/12h continuous infusion.” NCT06423898 ↗ “Cephalosporin- Ceftriaxone, (Ceftrisol Plus, Rocephin)” NCT05849090 ↗ “Cefotaxime 1-2g IV/8h ó ceftriaxone 1 g/12-24h” NCT02795949 ↗ “ceftriaxone and azithromycin capsules” NCT04461925 ↗ “Ceftriaxone 2 gm IV q12h for 3 days” NCT04999592 ↗ “IV ceftriaxone 2g or ampiclox 2g” NCT03518463 ↗ “Ceftriaxone : 1g/day parenteral” NCT06572761 ↗ “IV Ceftriaxone (Cephalosporin)” NCT05121974 ↗ “Ceftriaxone : 1g/j, 7j” NCT07030673 ↗ “Drug: Ceftriaxone” NCT01160640 ↗ “Ceftriaxone*” NCT02099240 ↗ “ceftriaxone” NCT05750966 ↗ |
| Known as | Anerning particle | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03675178 ↗ |
| Known as | Cefraden | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxon | “* Ceftriaxon : 1g to 2g/day in IV, IM or SC” NCT05074147 ↗ |
| Known as | Ceftriaxona | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone (as sodium) | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone disodium salt | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone disodium salt hemiheptahydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone sodium | “Anerning particle ,1 bag/time,3 times/ day, +ceftriaxone sodium,50mg/kg/time, 1 time/day, the total amount per day does not exceed 2g,for 10 days.When the condition is cured,...” NCT03675178 ↗10“Ceftriaxone sodium will be administered at a daily dose of 2 g (strength) when metronidazole is administered TID or at a daily dose of 4 g (strength) when metronidazole is...” NCT01473836 ↗ “Ceftriaxone sodium 2 g once daily intravenously plus metronidazole 1 g to 2 g daily given in divided doses intravenously.” NCT00230971 ↗ “Ceftriaxone sodium 2 g once daily intravenously plus metronidazole 1 g to 2 g daily given in divided doses intravenously.” NCT00195351 ↗ “Gonorrhea will be treated with a single dose of 250 mg of ceftriaxone sodium administered by intramuscular injection.” NCT00644150 ↗ “Intravenous injection of 500mg of ceftriaxone sodium (Rocephin®; Roche).” NCT03895567 ↗ “Comparator: ceftriaxone sodium /Duration of Treatment: 14 Days” NCT00451386 ↗ “Ceftriaxone sodium and Sulbactam Sodium for injection” NCT04202068 ↗ “Drug: Ceftriaxone Sodium” NCT05051163 ↗ |
| Known as | Ceftriaxone sodium anhydrous | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone sodium component of rocephin kit | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone sodium hydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftriaxone sodium sesquaterhydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Ceftrisol Plus | “Cephalosporin- Ceftriaxone, (Ceftrisol Plus, Rocephin)” NCT05849090 ↗ |
| Known as | CRO | “a single 1 g intravenous (IV) dose of ceftriaxone (CRO) plus doxycycline (DOX) versus a single 800 mg oral dose of cefixime (CFM) plus DOX for the treatment of NG-CT co-infection” PMID 35810277 ↗ Jul 2022 |
| Known as | CTRX | “intravenous MNZ combined with ceftriaxone (CTRX) in Japanese subjects” PMID 25442806 ↗ Nov 2014 |
| Known as | CTX | “In this pilot study, we aimed to assess the feasibility of a randomized study of whether prophylactic ceftriaxone (CTX), administered to hospitalized patients with advanced...” PMID 38180983 ↗ Jan 20242“ceftriaxone (CTX): 50 mg/kg q12h (max. 4 g per day)” NCT07484633 ↗ “ceftriaxone-metronidazole (CTX/MET)” PMID 22439781 ↗ Mar 2012 |
| Known as | Megion | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | RO 13-9904 | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | RO-13-9904/001 | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Rocefin | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Known as | Rocephin | “The treatment involves 10 weeks of either intravenous antibiotic called ceftriaxone (also known as Rocephin) or intravenous placebo (inactive substance).” NCT00037479 ↗6“Here, Ceftriaxone (Rocephin®) a third generation cephalosporin will be used” NCT05398081 ↗ “a 3-week course of ceftriaxone (Rocephin) IV injection (daily dose 2g/day)” NCT05821478 ↗ “Intravenous injection of 500mg of ceftriaxone sodium (Rocephin®; Roche).” NCT03895567 ↗ “Cephalosporin- Ceftriaxone, (Ceftrisol Plus, Rocephin)” NCT05849090 ↗ “Ceftriaxone (Rocephin®)” NCT06611111 ↗ “Ceftriaxone (Rocephin®)” NCT07229755 ↗ |
| Known as | Rocephin (ceftriaxone) | “Rocephin (ceftriaxone)” NCT04999592 ↗ |
| Known as | Sodium ceftriaxone, anhydrous | ChEMBL registry synonym — accepted as the source's own label CHEMBL161 ↗ |
| Action | Activate | “ceftriaxone increases EAAT2 activity” PMID 25297012 ↗ Oct 2014 |
| Modality | Other / unclassified | “cephalosporine : ceftriaxone by intra venous route” NCT00136656 ↗ |
| Route | Intravenous | “Ceftriaxone IV on day 1” NCT00004216 ↗ |