drugset / Trial / NCT04056806

2- Day vs. 5- Day Terlipressin and Ceftriaxone in the Control Acute Gastroesophageal Variceal Hemorrhage

NCT04056806

Phase 4 Unknown 100 enrolled E-DA Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

The use of prophylactic antibiotics in cirrhotics with gastrointestinal bleeding has been a routine clinical practice . It is still unknown whether use of short term vasoconstrictors and antibiotics could have superior acute hemostatic rate. Thus, the investigators conducted a trial to compare the effectiveness between participants receiving terlipressin and ceftriaxone 5 days and terlipressin and ceftriaxone 2 days after endoscopic therapy in cirrhotic patients presenting with acute gastro-esophageal variceal hemorrhage..

Timeline

Start
2019-08
Primary completion
2022-06
Completion
2022-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Ceftriaxone Other / unclassified 1 g Intravenous
Subject Terlipressin Peptide 1 mg