drugset / Trial / NCT06423898
Ampicillin and Ceftriaxone for the Treatment of Enterococcus Faecalis Infective Endocarditis.
Phase 4
Recruiting
284 enrolled
Andalusian Public Foundation for Health Research in Seville
Spanish Clinical Research Network - SCReN · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Phase IV, open-label, randomized and multicenter clinical trial to prove that patients with Enterococcus faecalis infective endocarditis treated with an antibiotic treatment as a continuous infusion is non-inferior to the standard treatment, usually administered in hospitalized patients.
Timeline
- Start
- 2024-10-09
- Primary completion
- 2027-07-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ampicillin | Unknown | 2 g | Intravenous |
| Subject | Ampicillin | Unknown | 12 g | Intravenous |
| Subject | Ceftriaxone | Other / unclassified | 2 g | Intravenous |
| Subject | Ceftriaxone | Other / unclassified | 4 g | Intravenous |