drugset / Trial / NCT06532409

Comparison of Efficacy of Oral Amoxicillin Versus Intravenous Ceftriaxone

NCT06532409

Not yet recruiting 114 enrolled RESnTEC, Institute of Research
RandomizedParallel-groupOpen-labelTreatment

Summary

The efficacy of oral amoxicillin is considered equal to that of ceftriaxone in community-acquired pneumonia among children. Also, there are some factors that contradict the usage of ceftriaxone, like antibiotic resistance, adverse reactions, drug cost, and the and the chances of IV trauma and infection, which is a major problem in developing countries. Therefore, this study was planned to determine the efficacy of oral amoxicillin compared with intravenous (IV) ceftriaxone in the treatment of uncomplicated ceftriaxone in community acquired pneumonia in children less than 5 years of age.

Timeline

Start
2024-10-01
Primary completion
2025-09-30
Completion
2025-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 100 mg/kg Intravenous
Subject Ceftriaxone Other / unclassified 75 mg/kg Intravenous

Indications