drugset
drugset / Trial / NCT00463840

Chemoradiation With Oxaliplatin and Fluorouracil (5FU) for Locally Advanced Pancreatic Cancer

NCT00463840 ↗

Phase 1/2 Terminated 24 enrolled NYU Langone Health Sanofi · collab
NaSingle-groupOpen-labelTreatment

Summary

The intention of this trial is to determine the maximum tolerated of the treatment combination and to evaluate its safety and efficacy.

Timeline

Start
2004-06
Primary completion
2010-07
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxaliplatin Small molecule 30 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 40 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 50 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 60 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 85 mg/m2 Intravenous
Subject fluorouracil Small molecule 200 mg/m2 Intravenous
Subject fluorouracil Small molecule 400 mg/m2 Intravenous
Subject fluorouracil Small molecule 2400 mg/m2 Intravenous
Background Leucovorin Small molecule 350 mg Intravenous

Indications

malignant pancreatic neoplasm