Efficacy and Safety of 17-Beta Estradiol in Treatment of Atrophic Vaginitis

Summary

This trial was conducted in the United States of America (USA). This trial aimed for a comparison between the effect of two different doses of estradiol on parameters related to efficacy and safety.

Timeline

Start

1994-08-31

Primary completion

1995-11-30

Completion

1995-11-30

Outcome

Met primary endpoint

paper Vaginal tablets with 25 mcg and 10 mcg E2 showed significant (P<.001) improvement in composite score of vaginal health. PMID 18165394 ↗

Publications

• Bachmann G, Lobo RA, Gut R, Nachtigall L, Notelovitz M. Efficacy of low-dose estradiol vaginal tablets in the treatment of atrophic vaginitis: a randomized controlled trial. Obstet Gynecol. 2008 Jan;111(1):67-76. doi: 10.1097/01.AOG.0000296714.12226.0f.

Drugs

Indications