drugset / Trial / NCT00467246

Sub-Cutaneous Insulin in Hyperglycaemic Emergencies

NCT00467246

RandomizedParallel-groupDouble-blindTreatment

Summary

Hyperglycaemic emergencies are associated with significant mortality (mortality in Diabetic Ketoacidosis 0.65 - 3.3% and in HyperOsmolar Non-Ketotic Coma 12 -17%). To reduce morbidity and mortality, prompt intervention and coma and close monitoring are essential. The study is designed to investigate whether a simple intervention with a long acting insulin can improve resolution of acidosis and hyperglycaemia, prevent recurrence of ketoacidosis and shorten hospital stay.

Timeline

Start
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject insulin detemir Protein / enzyme biologic Subcutaneous

Indications