drugset

drugset / Trial / NCT00467389

Use of Donepezil for Treatment of Cocaine Dependence

NCT00467389 ↗

Phase 2 Completed 12 enrolled US Department of Veterans Affairs

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to determine the safety of intravenous cocaine in subjects receiving oral donepezil.

Timeline

Start: 2007-02
Primary completion: 2008-09
Completion: 2008-09

Publications

Results Grasing K, Mathur D, Newton TF, DeSouza C. Donepezil treatment and the subjective effects of intravenous cocaine in dependent individuals. Drug Alcohol Depend. 2010 Feb 1;107(1):69-75. doi: 10.1016/j.drugalcdep.2009.09.010.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Donepezil	Small molecule	5 mg	Oral

Indications