drugset / Trial / NCT00475306

The Montefiore Metoclopramide Study

NCT00475306

Phase 4 Completed 289 enrolled Montefiore Medical Center
RandomizedFactorialQuadruple-blindTreatment

Summary

Metoclopramide is a dopamine antagonist frequently used for the treatment of nausea, vomiting, and migraine headaches in Emergency Departments. However, little research has focused on the optimal dose of metoclopramide for treatment of nausea in the emergency department. We propose a randomized, double-blind, placebo controlled trial to investigate the optimal dose of metoclopramide for treatment of nausea.

Timeline

Start
2007-05
Primary completion
2008-02
Completion
2008-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Diphenhydramine Unknown 25 mg Intravenous
Comparator Metoclopramide Small molecule 10 mg Intravenous
Comparator Metoclopramide Small molecule 20 mg Intravenous