drugset / Trial / NCT00475306
The Montefiore Metoclopramide Study
RandomizedFactorialQuadruple-blindTreatment
Summary
Metoclopramide is a dopamine antagonist frequently used for the treatment of nausea, vomiting, and migraine headaches in Emergency Departments. However, little research has focused on the optimal dose of metoclopramide for treatment of nausea in the emergency department. We propose a randomized, double-blind, placebo controlled trial to investigate the optimal dose of metoclopramide for treatment of nausea.
Timeline
- Start
- 2007-05
- Primary completion
- 2008-02
- Completion
- 2008-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Diphenhydramine | Unknown | 25 mg | Intravenous |
| Comparator | Metoclopramide | Small molecule | 10 mg | Intravenous |
| Comparator | Metoclopramide | Small molecule | 20 mg | Intravenous |