drugset / Trial / NCT00477659

Neural Correlates In Mild Alzheimer's Disease

NCT00477659

Phase 4 Completed 14 enrolled Eisai Inc. Pfizer · collab
NaSingle-groupOpen-labelTreatment

Summary

The objective of this study was to identify neural correlates of cognitive improvement after 3 months of donepezil hydrochloride treatment using either or both of two functional magnetic resonance imaging (fMRI) measures - the functional Hippocampus Connectivity Index (HCI) and Cerebral Blood Flow (CBF) Perfusion; in the Medial Temporal Lobe (MTL) network in subjects in the early stage of Alzheimer's Disease (AD).

Timeline

Start
2007-07-23
Primary completion
2008-08-15
Completion
2008-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Donepezil Small molecule 10 mg Oral

Indications