drugset / Trial / NCT00478452

Dendritic Cell Vaccine for High Risk Ovarian Cancer Patients

NCT00478452 ↗

RandomizedSingle-groupOpen-labelTreatment

Summary

This is a randomized Phase I/II study designed to assess the induction of an anti-tumor immune response; the effect of cyclophosphamide on the vaccine; and to assess safety in subjects with advanced ovarian cancer or primary serous peritoneal cancer given a multivalent DC vaccine, with or without a single dose of cyclophosphamide. Potential benefit may range from no direct benefit to the study participants to stimulation of the subject's own immune system to attack ovarian cancer to prevent relapse.

Timeline

Start
2005-08
Primary completion
2008-08
Completion
2008-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclophosphamide Other / unclassified 300 mg/m2 —
Subject DC Ova Vaccine — Other