Treatment of Hyperglycaemia and Insulin Resistance in HIV Infected Patients

Completed University Medical Centre Ljubljana

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate and compare the effects of treatment with rosiglitazone and metformin on insulin resistance in patients infected with Human Immunodeficiency Virus on stable Highly Active Antiretroviral Therapy including a Protease Inhibitor after the period of 48 weeks.

Timeline

Start: —
Primary completion: —
Completion: —

Publications

Silic A, Janez A, Tomazic J, Karner P, Vidmar L, Sharma P, Maticic M. Effect of rosiglitazone and metformin on insulin resistance in patients infected with human immunodeficiency virus receiving highly active antiretroviral therapy containing protease inhibitor: randomized prospective controlled clinical trial. Croat Med J. 2007 Dec;48(6):791-9. doi: 10.3325/cmj.2007.6.791.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Metformin	Small molecule	500 mg	—
Subject	Rosiglitazone	Small molecule	4 mg	—

Indications

No indication recorded.