drugset / Trial / NCT00485160
Ibuprofen vs. Continuous Indomethacin in the Treatment of PDA
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether closure of the PDA in premature neonates using IV ibuprofen vs continuous IV indomethacin has different side effects, eg. effects on renal function, on blood flow velocity in the superior mesenteric artery, the anterior cerebral artery, and the renal artery.
Timeline
- Start
- 2002-02
- Primary completion
- —
- Completion
- 2006-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ibuprofen | Small molecule | — | Intravenous |
| Subject | Indomethacin | Small molecule | — | Intravenous |