drugset / Trial / NCT00498966

Ph II Study of Perifosine for Patients With Carcinoma of the Kidney

NCT00498966

Phase 2 Completed 50 enrolled AEterna Zentaris
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase II study. Patients with kidney carcinoma will be considered in two groups. The goals of this study are: * To measure clinical benefit defined as tumor response or progression-free survival for more than 12 weeks in patients with metastatic carcinoma of the kidney who have failed or have progressed on a VEGF receptor inhibitor * To evaluate the safety of perifosine in patients with metastatic carcinoma of the kidney who have failed or have progressed on a VEGF receptor inhibitor

Timeline

Start
2007-07
Primary completion
2011-07
Completion
2011-10

Publications

  • Results Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 27, No 15S (May 20 Supplement), 2009: 5101

Drugs

EvaluationDrugModalityDoseRoute
Subject Perifosine Small molecule 100 mg Oral

Indications