Effect of Insulin Detemir on Use of Energy in Type 1 Diabetes

Phase 4 Terminated 23 enrolled Novo Nordisk A/S

RandomizedCrossoverOpen-labelTreatment

Summary

This trial is conducted in Europe. The purpose of this trial is to investigate if there is any change in the mechanism of energy expenditure (i.e. the way in which energy is used) in patients with type 1 diabetes, whilst taking two different, commercially available insulins for the treatment of their diabetes.

Timeline

Start: 2007-07
Primary completion: 2008-07
Completion: 2008-07

Publications

Results Zachariah S, Sheldon B, Shojaee-Moradie F, Jackson NC, Backhouse K, Johnsen S, Jones RH, Umpleby AM, Russell-Jones DL. Insulin detemir reduces weight gain as a result of reduced food intake in patients with type 1 diabetes. Diabetes Care. 2011 Jul;34(7):1487-91. doi: 10.2337/dc11-0098. Epub 2011 May 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	insulin NPH	Protein / enzyme biologic	—	Subcutaneous
Subject	insulin detemir	Protein / enzyme biologic	—	Subcutaneous
Background	insulin aspart	Protein / enzyme biologic	—	Subcutaneous

Effect of Insulin Detemir on Use of Energy in Type 1 Diabetes

Summary

Timeline

Publications

Drugs

Indications