drugset / Trial / NCT00530907

Valproic Acid and Bevacizumab in Patients With Advanced Cancer

NCT00530907

Phase 1 Completed 71 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to find the highest tolerable dose of bevacizumab in combination with valproic acid that can be given to patients with advanced cancer that has not responded to standard treatment or where there is no standard treatment for the disease. The safety of this drug combination will also be studied.

Timeline

Start
2007-06
Primary completion
2013-11
Completion
2013-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 2.5 mg/kg Intravenous
Background Valproic Acid Small molecule 5.3 mg/kg Oral

Indications

No indication recorded.