drugset / Trial / NCT00534183
Metabolic Profile and Anthropometric Changes in Schizophrenia
RandomizedParallel-groupDouble-blindScreening
Summary
"No clinical differences will be found between the three antipsychotics under study - olanzapine, risperidone and haloperidol - on the patients' metabolic profile and weight. "
Timeline
- Start
- 2006-06
- Primary completion
- —
- Completion
- 2006-12
Publications
- Ibragimov K, Keane GP, Carreno Glaria C, Cheng J, Llosa AE. Haloperidol (oral) versus olanzapine (oral) for people with schizophrenia and schizophrenia-spectrum disorders. Cochrane Database Syst Rev. 2024 Jul 3;7(7):CD013425. doi: 10.1002/14651858.CD013425.pub2.
- Saddichha S, Manjunatha N, Ameen S, Akhtar S. Effect of olanzapine, risperidone, and haloperidol treatment on weight and body mass index in first-episode schizophrenia patients in India: a randomized, double-blind, controlled, prospective study. J Clin Psychiatry. 2007 Nov;68(11):1793-8. doi: 10.4088/jcp.v68n1120.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Haloperidol | Other / unclassified | 10 mg | Oral |
| Comparator | Haloperidol | Other / unclassified | 20 mg | Oral |
| Subject | Olanzapine | Small molecule | 10 mg | Oral |
| Subject | Olanzapine | Small molecule | 20 mg | Oral |
| Comparator | Risperidone | Other / unclassified | 1 mg | — |
| Comparator | Risperidone | Other / unclassified | 6 mg | — |