drugset / Trial / NCT00537043

A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure

NCT00537043

Phase 1 Completed 24 enrolled GlaxoSmithKline
RandomizedSingle-groupOpen-labelTreatment

Summary

Carvedilol controlled release is a marketed drug to treat high blood pressure. This study is to compare carvedilol controlled release to carvedilol controlled release plus lisinopril (fixed-dose combination) after repeat dosing in patients with high blood pressure. This is to make sure that when carvedilol controlled release is given with lisinopril it acts the same in the body as when given alone. The study will also assess the safety and tolerability of the fixed-dose combination.

Timeline

Start
2007-10
Primary completion
2008-01
Completion
2008-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carvedilol Other / unclassified
Subject LISINOPRIL ANHYDROUS Small molecule