Steroids in the Maintenance of Remission of Proliferative Lupus Nephritis

Summary

There is debate as to whether long-term low-dose steroids such as prednisolone help to suppress relapses of systemic lupus erythematosus (SLE) in patients who are in remission from their lupus nephritis. If low-dose prednisolone reduces relapses, these beneficial effects may be counter-balanced by the long-term side-effects associated with prednisolone. This pilot study will determine the feasibility of conducting a larger randomized control trial that will answer the question of whether or not long-term low-dose prednisolone (5 - 7.5 mg/day) reduces the flares of SLE in patients with previous lupus nephritis.

Timeline

Start

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Primary completion

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Completion

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Outcome

Outcome not reported

Stopped: “Local pharmacy unwilling to comply with study protocol”

Drugs

Indications