A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy

Phase 1/2 Withdrawn Swedish Orphan Biovitrum Amgen · collab

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The purpose of this study is to evaluate the efficacy, safety and tolerability of palifermin on the incidence of oral mucositis in subjects with locally advanced head and neck cancer receiving postoperative radiotherapy.

Timeline

Start: 2007-10
Primary completion: 2008-09
Completion: 2008-09

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Palifermin	Protein / enzyme biologic	120 ug/kg	Intravenous

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy

Summary

Timeline

Drugs

Indications