Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

Phase 2/3 Completed 5659 enrolled Johns Hopkins University Sage Products, Inc. · collab

RandomizedCrossoverOpen-labelPrevention

Summary

The investigators propose to conduct a large clinical study to determine if daily bathing with chlorhexidine impregnated cloths will reduce the incidence of healthcare-associated infections in the Pediatric Intensive Care Unit (PICU).

Timeline

Start: 2008-02
Primary completion: 2010-12
Completion: 2012-06

Publications

Results Milstone AM, Elward A, Song X, Zerr DM, Orscheln R, Speck K, Obeng D, Reich NG, Coffin SE, Perl TM; Pediatric SCRUB Trial Study Group. Daily chlorhexidine bathing to reduce bacteraemia in critically ill children: a multicentre, cluster-randomised, crossover trial. Lancet. 2013 Mar 30;381(9872):1099-106. doi: 10.1016/S0140-6736(12)61687-0. Epub 2013 Jan 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chlorhexidine gluconate	Other / unclassified	2 %	Topical

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

Summary

Timeline

Publications

Drugs

Indications