drugset / Trial / NCT00553969
Efficacy of Coreg CR and Lisinopril on Markers for Cardiovascular Functional and Structural Disease
RandomizedFactorialQuadruple-blindTreatment
Summary
This study will examine the individual and combined effects of Coreg CR and lisinopril, on cardiovascular health as measured by Rasmussen Disease Score (RDS) in a blinded, placebo controlled comparison over a 9-month study period. Patients to be randomized will have pre-hypertensive blood pressures that do not require anti-hypertensive therapy and at least one additional cardiovascular risk factor.
Timeline
- Start
- 2007-11
- Primary completion
- 2010-09
- Completion
- 2010-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carvedilol | Other / unclassified | 40 mg | — |
| Subject | LISINOPRIL ANHYDROUS | Small molecule | 20 mg | — |