The Optimization of Procedural Pain Control in Intensive Care Unit (ICU) Patients

Completed 150 enrolled St. Antonius Hospital Erasmus Medical Center · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to determine the influence of morphine 2,5 mg or morphine 7,5 mg iv during a painful and unavoidable intervention in critically ill patients.

Timeline

Start: 2008-02
Primary completion: 2009-02
Completion: 2010-02

Publications

Goulooze SC, Krekels EH, Saleh MA, Ahlers SJ, Valitalo PA, van Dongen EP, van Schaik RH, Hankemeier T, Tibboel D, Knibbe CAJ. Predicting Unacceptable Pain in Cardiac Surgery Patients Receiving Morphine Maintenance and Rescue Doses: A Model-Based Pharmacokinetic-Pharmacodynamic Analysis. Anesth Analg. 2021 Mar 1;132(3):726-734. doi: 10.1213/ANE.0000000000005228.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Morphine	Other / unclassified	2.5 mg	Intravenous
Comparator	Morphine	Other / unclassified	7.5 mg	Intravenous

Indications

No indication recorded.