drugset / Trial / NCT00560391

Dasatinib in Combination With Revlimid (and Dexamethasone)

NCT00560391

Phase 1 Completed 35 enrolled Bristol-Myers Squibb
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study was to determine the safety and tolerability of dasatinib when given in combination with lenalidomide and a low dose dexamethasone for the treatment of relapsed or refractory multiple myeloma.

Timeline

Start
2008-05
Primary completion
2011-10
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified 15 mg
Subject Lenalidomide Other / unclassified 20 mg
Subject Lenalidomide Other / unclassified 25 mg
Subject dasatinib anhydrous Small molecule 70 mg
Subject dasatinib anhydrous Small molecule 100 mg
Subject dasatinib anhydrous Small molecule 140 mg
Background Dexamethasone Small molecule 40 mg

Indications