Continuous Infusion of Fentanyl in Preterm on MV

Summary

The objective of this randomized, double-blind trial is to compare the efficacy and safety of 2 therapeutic regimens of fentanyl administration in a population of preterm newborns of GA \<= 32 weeks in MV: * Group A) continuous infusion of Fentanyl + open label boluses of Fentanyl; * Group B) continuous infusion of placebo + open label boluses of Fentanyl.

Timeline

Start

2007-12

Primary completion

2010-04

Completion

2010-07

Publications

• Ancora G, Lago P, Garetti E, Pirelli A, Merazzi D, Mastrocola M, Pierantoni L, Faldella G. Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation. J Pediatr. 2013 Sep;163(3):645-51.e1. doi: 10.1016/j.jpeds.2013.02.039. Epub 2013 Apr 10.

Drugs

Indications